Alzheimer’s drug study gives ‘tantalising’ results

Source: BBC

By Caroline Parkinson

A drug that destroys the characteristic protein plaques that build up in the brains of patients with Alzheimer’s is showing “tantalising” promise, scientists say.

Experts are cautious because the drug, Aducanumab, is still in the early stages of development.

But a study in Nature has shown it is safe and hinted that it halts memory decline.

Larger studies are now under way to fully evaluate the drug’s effects.

The build-up of amyloid in the brain has been a treatment target for many years.

Dropped out

This study, of 165 patients, was designed to test Aducanumab was safe to take.

After a year of treatment, it also showed the higher the dose the stronger the effect on amyloid plaques.

The researchers then carried out tests on memory and found “positive effects”.

However, 40 people dropped out of the study, half because of side effects they experienced, such as headaches. These too were much more common with a higher dosage.

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