Shift workers beware: Sleep loss may cause brain damage, new research says

By Ben Brumfield

(CNN) — Are you a truck driver or shift worker planning to catch up on some sleep this

weekend?

Cramming in extra hours of shut-eye may not make up for those lost pulling all-nighters, new research indicates.

The damage may already be done — brain damage, that is, said neuroscientist Sigrid Veasey from the University of Pennsylvania.

The widely held idea that you can pay back a sizeable “sleep debt” with long naps later on seems to be a myth, she said in a study published this week in the Journal of Neuroscience.

Long-term sleep deprivation saps the brain of power even after days of recovery sleep, Veasey said. And that could be a sign of lasting brain injury.

Veasey and her colleagues at the University of Pennsylvania medical school wanted to find out, so, they put laboratory mice on a wonky sleep schedule that mirrors that of shift workers.

They let them snooze, then woke them up for short periods and for long ones.

Then the scientists looked at their brains — more specifically, at a bundle of nerve cells they say is associated with alertness and cognitive function, the locus coeruleus.

They found damage and lots of it.

“The mice lose 25% of these neurons,” Veasey said.

This is how the scientists think it happened.

When the mice lost a little sleep, nerve cells reacted by making more of a protein, called sirtuin type 3, to energize and protect them.

But when losing sleep became a habit, that reaction shut down. After just a few days of “shift work” sleep, the cells start dying off at an accelerated pace.

Read further

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.