Oxford, AstraZeneca Begin Advanced Trials of Covid Vaccine


Oxford university. The Muslim Times has the best collection of articles for the war against Covid 19, especially the vaccines.

Source: Bloomberg

The University of Oxford and AstraZeneca Plc have begun recruiting more than 10,000 subjects for advanced human studies of one of the world’s fastest-moving experimental Covid-19 vaccines.

A smaller part of the trial will expand the age range of testing to children from 5 to 12 years old and adults 56 and older, according to a statement. The other, larger stage will test the vaccine’s effectiveness in volunteers 18 and older.

Companies around the world are racing to develop weapons to fight the pandemic that has cloistered large populations and battered economies. AstraZeneca received a boost in its efforts to get the immunization tested and ready for use when the U.S. pledged as much as $1.2 billion toward development on Thursday.

Adult subjects in the studies will be randomly chosen to receive one or two doses of the Oxford candidate or an already licensed vaccine against meningococcus for comparison.

The volunteers will be recruited across the U.K. and will record their reactions in an e-diary and attend some follow-up visits. Some will be given swabs for taking samples at home.

The proposed Covid-19 vaccine is made from a weakened version of a common cold virus that’s genetically changed to make it unable to grow in humans. More than 1,000 people have already received it in an early-stage trial that began in April.

Astra plans to make as many as 30 million doses available in Britain as early as September. Under its agreement with Astra, the U.S. could begin receiving supplies as early as October.

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Categories: The Muslim Times, Vaccine

4 replies

  1. Wikimedia Commons

    The head of the Oxford Vaccine Group said Friday that clinic trials on its vaccine for the coronavirus are “progressing very well.”

    1,000 people have already been inoculated. The next stage will see 10,000 more given the treatment through May and June, Andrew Pollard said.

    The trial vaccine is called as AZD1222 or ChAdOx1 nCoV-19. It was first tested on humans on April 23, following success in macaque monkeys.

    The group said they hoped for clinical test results in two months, but that it could take as long as six.

    Visit Business Insider’s homepage for more stories.

    The head of the Oxford Vaccine Group said Friday that its clinical trials are “progressing very well” and that the program will inoculate 10,000 new people.

    “We are now initiating studies to evaluate how well the vaccine induces immune responses in older adults,” Professor Andrew Pollard, head of the Oxford Vaccine Group, said in a press release.

    ‘The clinical studies are progressing very well.”

    The trial vaccine is called AZD1222 or ChAdOx1 nCoV-19. It was first tested on two humans on April 23 in Oxford, following promising results on six macaque monkeys in the US in March.

    1,000 people have since been given the trial vaccine across the UK, but children and those over 55 were excluded.

    10,260 new people, including the elderly, will be given the trial vaccine in May and June, the group said. Subjects keep a diary and submit regular blood samples.


  2. May 21 (Reuters) – The U.S. government has ordered 300 million doses of a potential COVID-19 virus being developed by AstraZeneca and Oxford University and hopes first doses can be made available by October, the Department of Health and Human Services said on Thursday.

    “This contract with AstraZeneca is a major milestone in Operation Warp Speed’s work toward a safe, effective, widely available vaccine by 2021,” HHS Secretary Alex Azar said in a statement. (Reporting by Aakash Jagadeesh Babu in Bengaluru; editing by Patrick Graham)


  3. Children and older adults are to be included in the second phase of vaccine trials to protect against coronavirus.

    The first phase of the University of Oxford trial began in April, involving 1,000 healthy adults aged 55 and under.

    Now more than 10,200 people – including over 70s and five to 12-year-olds – will be enrolled in the study, to see the effects on their immune system.

    Trials of the same vaccine on monkeys appear to have given them some protection against the disease.

    The animals had less of the virus in their lungs and airways, but it is not certain this finding will translate to people.

    The scientists behind the vaccine have previously said they are aiming to have at least a million doses of a coronavirus vaccine by September this year.

    But the UK government has repeatedly said there are no guarantees – and a vaccine could still be some way off.

    And most experts still estimate it will take 12 to 18 months to develop and manufacture a vaccine.

    There are more than 100 experimental vaccines against Covid-19 currently being developed worldwide.


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