A small study in 19 people suggested a drug from AstraZeneca Plc’s arsenal of cancer treatments may be repurposed to help Covid-19 patients experiencing extreme immune reactions.
Many patients with Covid-19 suffer from an inflammatory condition, sometimes called cytokine storm, when the immune system overreacts to the virus. Astra’s drug, Calquence, belongs to a class known as BTK inhibitors that target a protein that affects inflammation, and may help quell the complication.
Nine of 11 hospitalized patients who initially needed oxygen were able to leave the hospital after getting Calquence, which is approved to treat lymphoma. Of the remaining two patients one is still hospitalized, while the other died.
Among eight patients who needed mechanical ventilation, four were taken off breathing apparatuses by the end of their treatment and no longer required additional oxygen, while the other four died. The drug will need to be tested in a larger study and compared against a placebo to confirm its value. AstraZeneca has started two mid-stage studies of the medicine in hospitalized patients experiencing cytokine storm.
The best of the Muslim Times’ collection for war against Covid 19:
In this day and age, understanding bacteria and viruses and developing vaccines are national security issues. In my view sizable part of every country’s defense budget should be spent in these pursuits rather than making tanks and other weapons.
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DAILY NEW CASES AND DEATHS IN US, CDC SITE