Epigraph:
Every human life is precious and sacred and saving one life is like saving the whole of humanity. (Al Quran 5:32/33)
University of Pittsburgh. Our favorite posts: The Muslim Times Recommending Universal BCG Vaccination to Fight the Pandemic and A Moonshot Moment for the Muslims: Making Covid 19 Vaccine before the West and China
Source: Science Alert
By Vicotr Tangermann
Researchers at the University of Pittsburgh School of Medicine announced today that they have developed a promising new COVID–19 vaccine candidate.
Early animal trials have shown promise so far, but human trials are still in the planning stages. The researchers already had a big leg up from past epidemics.
“We had previous experience on SARS-CoV in 2003 and MERS-CoV in 2014,” said Andrea Gambotto, co-senior author of the peer-reviewed paper published in the journal EBioMedicine, and associate professor of surgery at the Pittsburgh School of Medicine, in a statement.
“These two viruses, which are closely related to SARS-CoV–2, teach us that a particular protein, called a spike protein, is important for inducing immunity against the virus,” Gambotto explained. “We knew exactly where to fight this new virus.”
The vaccine dubbed “PittCoVacc” (Pittsburgh Coronavirus Vaccine) works in the same basic way as a flu shot: By injecting lab-made pieces of viral protein into the body to help it build an immunity.
When tested in mice, the researchers found that the number of antibodies capable of neutralizing the deadly SARS-CoV–2 virus surged two weeks after delivery.
Instead of being delivered through a needle, the new drug is administered through a microneedle array, a Band-Aid like patch made up of 400 tiny microneedles. Once the patch is applied, the microneedles, which are made entirely of sugar and protein dissolve, leaving no trace behind.
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Categories: Health