Source: WSJ
AstraZeneca AZN 1.24% PLC said Saturday clinical trials for its experimental coronavirus vaccine have resumed in the U.K. after regulators concluded it was safe to do so, following a pause in studies globally after a person who received the vaccine had an unexplained illness.
Trials in other countries, including the U.S., remain paused while AstraZeneca works with national health authorities, the company said.
AstraZeneca said Tuesday it paused trials globally of a vaccine it licensed from the University of Oxford after a vaccinated woman in the U.K. experienced the unexplained illness, which a U.S. official described as a spinal cord problem.
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For the latest news about drugs and vaccines’ trials please go to: Pharmaceutical-Technology
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Categories: Vaccine
Also Saturday, Pfizer Inc. PFE and partner BioNTech SE said they asked U.S. regulators to permit expanding the late-stage trial testing for their experimental Covid-19 vaccine to about 44,000 people, up from 30,000.
https://www.wsj.com/articles/astrazeneca-covid-19-vaccine-trials-resume-in-the-u-k-11599922981?mod=hp_lead_pos1
Australia says it will secure almost 85 million doses of a coronavirus vaccine if two promising trials prove successful.
Prime Minister Scott Morrison said the country had struck two deals that would allow free doses to be rolled out in 2021 if they were approved for use.
Mr Morrison estimated the cost to be A$1.7bn (£0.9bn; $1.24bn).
Australia’s 25 million people could begin receiving doses from January but there were “no guarantees”, he said.
“However the agreement puts Australia at the top of the queue, if our medical experts give the vaccines the green light,” the prime minister said.
One vaccine is from Oxford University and pharmaceutical company AstraZeneca, while the other is a local one from the University of Queensland and CSL. Both would most likely require people to take two doses.
https://www.bbc.com/news/world-australia-54052430
Reblogged this on Alexanders' Blog.
The vaccine is now named AZD1222 and is co-invented by the University of Oxford and its spin-out company, Vaccitech. The vaccine uses a replication-deficient chimpanzee viral vector based on a weakened version of a common cold virus (adenovirus) and contains the genetic material of the SARS-CoV-2 virus spike protein. After vaccination, the surface spike protein is produced, priming the immune system to attack the SARS-CoV-2 virus if it later infects the body, explains the company statement.
“The company will continue to work with health authorities across the world and be guided as to when other clinical trials can resume to provide the vaccine broadly, equitably and at no profit during this pandemic,” AstraZeneca said.
https://weather.com/en-IN/india/coronavirus/news/2020-09-13-oxford-astrazeneca-covid-19-vaccine-trials-indian-trials-resume