Vaccine Candidate Delivers Protection In A Single Shot (In Monkeys)

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The Muslim Times has the best collection of articles for the war against Covid 19, especially the vaccines.

Source: NPR

Nobody is eager to be stuck by a needle twice, so naturally many would view a COVID-19 vaccine that provides disease protection after a single injection as a good thing.

Two new studies released today suggest that might be possible.

Both studies involved rhesus macaque monkeys. In one study, researchers from Beth Israel Deaconess Medical Center and pharmaceutical company Janssen injected either with a vaccine candidate or an inert placebo. Six weeks after they were vaccinated, the researchers exposed the animals to the coronavirus, both by putting it in their noses and down their throats.

All 20 of the animals receiving the inert, placebo injection showed signs of infection in both their lungs and noses after being exposed to the virus. But one of the vaccine candidates seemed quite effective in preventing infection. In the six animals vaccinated with this particular candidate, none had signs of infection in their lungs, and only one had a sign of infection in the nose.

This is the candidate Janssen’s parent company, Johnson & Johnson has decided to start testing in humans. Initial trials started this week.

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In this day and age, understanding bacteria and viruses and developing vaccines are national security issues. In my view sizable part of every country’s defense budget should be spent in these pursuits rather than making tanks and other weapons.

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Categories: The Muslim Times, Vaccine

2 replies

  1. J&J vaccine protected monkeys with single dose, new study finds

    Johnson & Johnson on Thursday released new details of a study that showed its best-performing vaccine candidate provided monkeys with strong protection from the virus with just one dose, Reuters reported. Many other vaccines in development currently require two doses.

    The positive results prompted the U.S.-based pharmaceutical company to start human trials for the drug on Thursday, according to Reuters.

    “This gives us confidence that we can test a single-shot vaccine in this epidemic and learn whether it has a protective effect in humans,” Dr. Paul Stoffels, J&J’s chief scientific officer, told Reuters.

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