Coronavirus: UK authorises anti-viral drug remdesivir

National Health service

The Muslim Times has the best collection of articles for the war against Covid 19, especially the vaccines.

Source: BBC

By Michelle Roberts, Health editor, BBC News online

A drug treatment called remdesivir that appears to shorten recovery time for people with coronavirus is being made available on the NHS.

Health Secretary Matt Hancock said it was probably the biggest step forward in the treatment of coronavirus since the crisis began.

Remdesivir is an anti-viral medicine that has been used against Ebola.

UK regulators say there is enough evidence to approve its use in selected Covid-19 hospital patients.

For the time being and due to limited supplies, it will go to those most likely to benefit.

The US and Japan have already made similar urgent arrangements to provide early access to the medicine before they have a marketing agreement.

The drug is currently undergoing clinical trials around the world, including in the UK.

Early data suggests it can cut recovery time by about four days, but there is no evidence yet that it will save more lives.

It is not clear how much stock pharmaceutical company Gilead Sciences has available to treat UK patients.

Allocation of the intravenous drug will be based on the advice of doctors.

Minister for Innovation Lord Bethell said: “This shows fantastic progress. As we navigate this unprecedented period, we must be on the front foot of the latest medical advancements, while always ensuring patient safety remains a top priority.

“The latest, expert scientific advice is at the heart of every decision we make, and we will continue to monitor remdesivir’s success in clinical trials across the country to ensure the best results for UK patients.”

Dr Stephen Griffin from the University of Leeds Medical School, said it was perhaps the most promising anti-viral for coronavirus so far.

He said patients with the most severe disease would be likely to receive it first. “Whilst this is clearly the most ethically sound approach, it also means that we ought not to expect the drug to immediately act as a magic bullet.

“We can instead hope for improved recovery rates and a reduction in patient mortality, which we hope will benefit as many patients as possible.”

Other drugs being investigated for coronavirus include those for malaria and HIV.

Testing of the malaria drug hydroxychloroquine has been halted in some trials because of safety fears.

The World Health Organization says the temporary suspension is a precaution, after a recent medical study found the drug might increase the risk of death and heart rhythm complications.

In the UK, the Recovery trial looking at using this drug in patients remains open, but another one, using it in frontline NHS staff to prevent rather than treat infections, has paused recruiting more volunteers.

Reference

The best of the Muslim Times’ collection for war against Covid 19:

In this day and age, understanding bacteria and viruses and developing vaccines are national security issues. In my view sizable part of every country’s defense budget should be spent in these pursuits rather than making tanks and other weapons.

For the latest news about drugs and vaccines’ trials please go to: Pharmaceutical-Technology

For the latest health news from BBC, Please click here

Novavax starting human trial of its vaccine in Australia

Kaiser Permanente launches first coronavirus vaccine trial

Corona Fear’s Cure: Chanting from the Bible and the Quran

Can You Chant from the Bible or the Quran to Bliss and Happiness?

Japanese flu drug ‘clearly effective’ in treating coronavirus, says China

Synthetic antibodies might offer a quick coronavirus treatment

The Four Possible Timelines for Life Returning to Normal

The Muslim Times Recommending Universal BCG Vaccination to Fight the Pandemic

Coronavirus: TB Vaccination Trial Started in Melbourne, Australia

The Muslim Times has the best collections in the war against Covid 19 as we are collecting from all the established sources

All of humanity are intimate neighbors: Coronavirus proves it once again

Praise be to God for the Miracle of Our Immune System

USA: 15-minute coronavirus test is here

Does the Ordinary Soap Kill Coronavirus?

Here’s a list of disinfectants you can use against coronavirus

For the number of cases and epidemiology in each country go to: WorldOMeters

DAILY NEW CASES AND DEATHS IN US, CDC SITE

1 reply

  1. A large federal trial of remdesivir has entered its next phase, in which researchers will test the effects of combining the antiviral drug with a pill to bring down inflammation.

    The pill, called baricitinib, was approved in 2018 to treat rheumatoid arthritis.

    Full coverage of the coronavirus outbreak

    Remdesivir, manufactured by Gilead Sciences, is the only treatment that’s been shown in a clinical trial to have an effect on COVID-19 so far. Preliminary results from that trial, which included sites worldwide, published Friday in The New England Journal of Medicine, found that the drug reduced patients’ length of hospital stay by about four days, from 15 days, on average, to 11 days. More than 1,000 patients hospitalized with COVID-19 received either remdesivir or a placebo.

    The ongoing trial, which is sponsored by the National Institute of Allergy and Infectious Diseases, did not show the drug had a significant impact on deaths. However, researchers said the shortened hospital stays was an important finding.

    “Four days being sick in a hospital receiving major care, being intubated, receiving oxygen, is an eternity,” Dr. Andre Kalil, a principal investigator for the trial at the University of Nebraska Medical Center in Omaha, said.

    “The longer you stay in the hospital, the higher the chances of forming blood clots,” Kalil told NBC News. “The longer you stay in a hospital, the higher the chance of getting hospital-acquired infections.”

    Still, it’s clear remdesivir on its own will not be enough to make a considerable impact on cases of COVID-19. For the next phase of the trial, all patients will receive remdesivir. Half will also get baricitinib, and the other half will get a placebo. Researchers anticipate 600 to 700 patients will be recruited.

    https://www.nbcnews.com/health/health-news/federal-remdesivir-trial-enters-second-phase-here-s-what-s-n1214941

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.