Source: BBC
Pakistani PM Nawaz Sharif is due to meet President Barack Obama in the White House seeking an end to drone strikes and the formation of a new post-Afghanistan war relationship.
But correspondents say that few breakthroughs are expected on contentious issues on their agenda.
The US is unlikely to offer any assurances on its secretive and controversial drone programme.
Relations between Islamabad and Washington nosedived two years ago.
In May 2011 al-Qaeda leader Osama Bin Laden was killed by US special forces at his his hideout in Abbottabad in north-eastern Pakistan without the Pakistani government receiving prior warning from Washington.
Relations were further strained by the killing of 24 Pakistani troops in a US air strike along the Afghan border later in 2011.
“We want to find ways for our countries to co-operate, even as we have differences on some issues, and we want to make sure that the trajectory of this relationship is a positive one,” White House spokesman Jay Carney said.
Mr Sharif said on Tuesday that drone strikes had “deeply disturbed and agitated” Pakistani people and that his government was committed to bringing them to an end.
Wikileaks tells us that in fact the Pakistani Government always agreed to the drones program. They stated in private to the Americans “you do what you like but in public we will protest”.